For Jnana’s PKU program there were multiple points of intervention that RapidFire-MS enabled. These points included a cellular amino acid transport assay, liver microsome stability, and other in vitro ADME assays. The use of the RapidFire-MS greatly increased medicinal chemistry cycle times, directly impacting the timeline to a clinical development candidate.

Key Learning Objectives:

• Impact that the speed of the RapidFire enabled on Jnana’s programs
• Versatility of the RapidFire to support the RAPID platform and internal projects
• What type of expertise required to bring RapidFire in-house