Analysis of Polar Analytes by LC – What are the Options?
Separation of highly polar compounds such as pharmaceuticals, metabolites, and biomarkers can be challenging using traditional reversed-phase methods on regular C18 columns. In this webinar, we will discuss available alternatives such as ion pairing, use of polar bonded phases, or polar modified columns. We will also discuss the benefits of selecting alternative modes of separation, such as HILIC and Ligand Exchange chromatography.